Association between dietary consumption of fatty acids and age-related macular degeneration in the National Health and Nutrition Examination Survey
Mitchell, P., Liew, G., Gopinath, B. & Wong, T. Y. Age-related macular degeneration. Lancet 392, 1147 (2018).
Google Scholar
Wong, W. L. et al. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: A systematic review and meta-analysis. Lancet Glob. Health 2, e106 (2014).
Google Scholar
Moutray, T. & Chakravarthy, U. Age-related macular degeneration: Current treatment and future options. Ther. Adv. Chronic Dis. 2, 325 (2011).
Google Scholar
Fritsche, L. G. et al. Age-related macular degeneration: Genetics and biology coming together. Annu. Rev. Genom. Hum. Genet. 15, 151 (2014).
Google Scholar
Chapman, N. A., Jacobs, R. J. & Braakhuis, A. J. Role of diet and food intake in age-related macular degeneration: A systematic review. Clin. Exp. Ophthalmol. 47, 106 (2019).
Google Scholar
Calder, P. C. Functional roles of fatty acids and their effects on human health. JPEN J. Parenter. Enteral Nutr. 39, 18S (2015).
Google Scholar
Bazan, N. G. Cell survival matters: Docosahexaenoic acid signaling, neuroprotection and photoreceptors. Trends Neurosci. 29, 263 (2006).
Google Scholar
Schnebelen, C. et al. Nutrition for the eye: Different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation. Ophthalmic Res. 41, 216 (2009).
Google Scholar
Age-Related Eye Disease Study 2 (AREDS2) Research Group. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA 309, 2005 (2013).
Google Scholar
Sangiovanni, J. P. et al. omega-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study. Am. J. Clin. Nutr. 90, 1601 (2009).
Google Scholar
Wu, J. et al. Dietary intakes of eicosapentaenoic acid and docosahexaenoic acid and risk of age-related macular degeneration. Ophthalmology 124, 634 (2017).
Google Scholar
Christen, W. G., Schaumberg, D. A., Glynn, R. J. & Buring, J. E. Dietary ω-3 fatty acid and fish intake and incident age-related macular degeneration in women. Arch. Ophthalmol. 129, 921 (2011).
Google Scholar
Arslan, S., Kadayifçilar, S. & Samur, G. The potential role of dietary antioxidant capacity in preventing age-related macular degeneration. J. Am. Coll. Nutr. 38, 424 (2019).
Google Scholar
SanGiovanni, J. P., Agrón, E., Clemons, T. E. & Chew, E. Y. Omega-3 long-chain polyunsaturated fatty acid intake inversely associated with 12-year progression to advanced age-related macular degeneration. Arch. Ophthalmol. 127, 110 (2009).
Google Scholar
Ho, L. et al. Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and ω-3 fatty acids: The Rotterdam study. Arch. Ophthalmol. 129, 758 (2011).
Google Scholar
Seddon, J. M. et al. Dietary fat and risk for advanced age-related macular degeneration. Arch. Ophthalmol. 119, 1191 (2001).
Google Scholar
van Asten, F. et al. No CFH or ARMS2 interaction with omega-3 fatty acids, low versus high zinc, or β-carotene versus lutein and zeaxanthin on progression of age-related macular degeneration in the age-related eye disease study 2: Age-Related Eye Disease Study 2 Report No. 18. Ophthalmology 126, 1541 (2019).
Google Scholar
Souied, E. H. et al. Oral docosahexaenoic acid in the prevention of exudative age-related macular degeneration: The Nutritional AMD Treatment 2 study. Ophthalmology 120, 1619 (2013).
Google Scholar
Sasaki, M. et al. Dietary saturated fatty acid intake and early age-related macular degeneration in a Japanese population. Investig. Ophthalmol. Vis. Sci. 61, 23 (2020).
Google Scholar
Roh, M. et al. Higher intake of polyunsaturated fatty acid and monounsaturated fatty acid is inversely associated with AMD. Investig. Ophthalmol. Vis. Sci. 61, 20 (2020).
Google Scholar
Yasukawa, T. et al. Association between fatty acid intakes and age-related macular degeneration in a Japanese population: JPHC-NEXT eye study. Transl. Vis. Sci. Technol. 12, 3 (2023).
Google Scholar
Klein, R. et al. The Wisconsin age-related maculopathy grading system. Ophthalmology 98, 1128 (1991).
Google Scholar
Flores, R., Carneiro, Â., Vieira, M., Tenreiro, S. & Seabra, M. C. Age-related macular degeneration: Pathophysiology, management, and future perspectives. Ophthalmologica 244, 495 (2021).
Google Scholar
Heesterbeek, T. J., Lorés-Motta, L., Hoyng, C. B., Lechanteur, Y. & den Hollander, A. I. Risk factors for progression of age-related macular degeneration. Ophthalmic Physiol. Opt. 40, 140 (2020).
Google Scholar
(2) Classification and diagnosis of diabetes. Diabetes Care 38(Suppl S8) (2015).
Whelton, P. K. et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J. Am. Coll. Cardiol. 71, e127 (2018).
Google Scholar
Aranceta, J. & Pérez-Rodrigo, C. Recommended dietary reference intakes, nutritional goals and dietary guidelines for fat and fatty acids: a systematic review. Br. J. Nutr. 107(Suppl 2), S8 (2012).
Google Scholar
Lawrenson, J. G. & Evans, J. R. Omega 3 fatty acids for preventing or slowing the progression of age-related macular degeneration. Cochrane Database Syst. Rev. 2015, CD10015 (2015).
Weikel, K. A., Chiu, C. J. & Taylor, A. Nutritional modulation of age-related macular degeneration. Mol. Aspects Med. 33, 318 (2012).
Google Scholar
Augood, C. et al. Oily fish consumption, dietary docosahexaenoic acid and eicosapentaenoic acid intakes, and associations with neovascular age-related macular degeneration. Am. J. Clin. Nutr. 88, 398 (2008).
Google Scholar
Swenor, B. K., Bressler, S., Caulfield, L. & West, S. K. The impact of fish and shellfish consumption on age-related macular degeneration. Ophthalmology 117, 2395 (2010).
Google Scholar
Zhong, Y. et al. Dietary fatty acid intake, plasma fatty acid levels, and the risk of age-related macular degeneration (AMD): A dose-response meta-analysis of prospective cohort studies. Eur. J. Nutr. 60, 3013 (2021).
Google Scholar
van Leeuwen, E. M. et al. A new perspective on lipid research in age-related macular degeneration. Prog. Retin. Eye Res. 67, 56 (2018).
Google Scholar
Agrón, E. et al. Dietary nutrient intake and progression to late age-related macular degeneration in the age-related eye disease studies 1 and 2. Ophthalmology 128, 425 (2021).
Google Scholar
Merle, B. et al. Plasma long-chain omega-3 polyunsaturated fatty acids and macular pigment in subjects with family history of age-related macular degeneration: The Limpia Study. Acta Ophthalmol. 95, e763 (2017).
Google Scholar
Ng, A. L. et al. Dietary habits, fatty acids and carotenoid levels are associated with neovascular age-related macular degeneration in Chinese. Nutrients 11, 1720 (2019).
Google Scholar
Rahmawaty, S., Charlton, K., Lyons-Wall, P. & Meyer, B. J. Dietary intake and food sources of EPA, DPA and DHA in Australian children. Lipids 48, 869 (2013).
Google Scholar
Guo, X. F., Li, X., Shi, M. & Li, D. n-3 Polyunsaturated fatty acids and metabolic syndrome risk: A meta-analysis. Nutrients 9, 703 (2017).
Google Scholar
Del, G. L. et al. ω-3 Polyunsaturated fatty acid biomarkers and coronary heart disease: Pooling Project of 19 Cohort Studies. JAMA Intern. Med. 176, 1155 (2016).
Google Scholar
Hino, A. et al. Very long chain N-3 fatty acids intake and carotid atherosclerosis: An epidemiological study evaluated by ultrasonography. Atherosclerosis 176, 145 (2004).
Google Scholar
Tian, Y. et al. Docosapentaenoic acid (22:5n–3) downregulates mRNA expression of pro-inflammatory factors in LPS-activated murine macrophage like RAW264.7 cells. J. Oleo Sci. 66, 1149 (2017).
Google Scholar
Drouin, G., Rioux, V. & Legrand, P. The n-3 docosapentaenoic acid (DPA): A new player in the n-3 long chain polyunsaturated fatty acid family. Biochimie 159, 36 (2019).
Google Scholar
Ren, J. et al. Long-chain polyunsaturated fatty acids and their metabolites regulate inflammation in age-related macular degeneration. J. Inflamm. Res. 15, 865 (2022).
Google Scholar
Tan, J. S., Wang, J. J., Flood, V. & Mitchell, P. Dietary fatty acids and the 10-year incidence of age-related macular degeneration: The Blue Mountains Eye Study. Arch. Ophthalmol. 127, 656 (2009).
Google Scholar
Chong, E. W. et al. Fat consumption and its association with age-related macular degeneration. Arch. Ophthalmol. 127, 674 (2009).
Google Scholar
Mares-Perlman, J. A. et al. Dietary fat and age-related maculopathy. Arch. Ophthalmol. 113, 743 (1995).
Google Scholar
Widmer, R. J., Flammer, A. J., Lerman, L. O. & Lerman, A. The Mediterranean diet, its components, and cardiovascular disease. Am. J. Med. 128, 229 (2015).
Google Scholar
Kennedy, E. T., Bowman, S. A. & Powell, R. Dietary-fat intake in the US population. J Am. Coll. Nutr. 18, 207 (1999).
Google Scholar
Aoki, A. et al. Dietary n-3 fatty acid, α-tocopherol, zinc, vitamin D, vitamin C, and β-carotene are associated with age-related macular degeneration in Japan. Sci. Rep. 6, 20723 (2016).
Google Scholar
Karger, A. B. et al. Association of plasma ω-3 fatty acids with early age-related macular degeneration in the multi-ethnic study of atherosclerosis. Retina 42, 1384 (2022).
Google Scholar
link